Malpetti and colleagues examined the relationship between tau pathology measured with 18F-AV-1451 (also known as 18F-flortaucipir or [18F]T807) PET scan, neuroinflammation detected by 11C-PK11195 PET imaging, brain atrophy studied with MRI, and longitudinal cognitive changes over 3 years in 12 patients with a clinical diagnosis of probable Alzheimer’s disease and 14 with a positive amyloid PET imaging amnestic MCI [14]. Here, MAPT is linked to Brain atrophy.