An important step forward in the differential diagnosis between corticobasal syndrome (CBS) subtypes is the feasibility of using [18F]PI-2620, which stands out for its less off-target binding to monoamine oxidases, relevant affinity to three repeats/four repeats (3R/4R) tau in AD, and affinity also for 4R tau in PSP [62]. This evidence concerns the gene MAPT and supranuclear palsy, progressive, 1.