Temperature did not impact basal (IVGTT day) plasma glucose (p = 0.51) or NEFA (p = 0.56) concentrations, while the basal plasma insulin concentration was greater in HE-treated sheep (4.48 vs. 8.17 mU/L, SED 1.265, p = 0.026). This evidence concerns the gene INS and hereditary elliptocytosis.