Until now, only a few research studies have investigated the efficacy of CEUS in studying ovarian vascularization: the behavior of ovarian lesions (tumors or tumor-like) in women [79], functional ovarian vascular changes induced by GnRH-analogue administration in a murine model [80], and in other experimental conditions in rhesus monkeys [81]. This evidence concerns the gene GNRH1 and neoplasm.