Concerning sphingolipid levels, RSV alters their balance towards an increase in CER levels through the enhancement of CER levels and the induction of apoptosis, as observed in colon, breast and prostate cancer cells, as well as the downregulation of SK1 expression and activity, as evidenced in prostate cancer cells [113,117,118,119]. The gene discussed is SPHK1; the disease is prostate carcinoma.