ApoD expression has been shown to be increased in the regenerated and remyelinating sciatic nerves [43,72], and in various injuries of the nervous system associated with stroke [130,131], entorhinal cortex lesion [132], traumatic brain injuries [133], coronavirus OC43 encephalitis [22] and experimental kainic acid induced lesions [134]. The gene discussed is APOD; the disease is viral encephalitis.