In addition, co-treatment with PA and NAC reduced endothelial dysfunction, including restoration of total antioxidant capacity, cell viability, NO levels, and eNOS, DRP1, MFN2, NDUFS3, and UQCRC1 protein levels, as well as inhibition of IL6 and CHOP mRNA levels (Figure 6b–h). Here, DDIT3 is linked to endothelial dysfunction.