CRP and ventilator-associated pneumonia: For example, the diagnostic value of single measurements performed for PCT (procalcitonin), a prohormone released in serum in response to inflammation, CRP (C-reactive Protein), an acute-phase protein and soluble triggering receptor expressed on myeloid cells and s-TREM biomarker, a glycoprotein member of the immunoglobulin family up-regulated in the presence of pathogens, has not been demonstrated as they cannot discriminate between suspected VAP and non-VAP cases [10,11,12].