Strategies to prevent rhinovirus infection have included the use of recombinant soluble ICAM-1 as a decoy receptor able to inhibit infection [181] or the use of a monoclonal anti-ICAM-1 antibody, which blocks binding of rhinovirus to ICAM-1 without preventing the interaction between ICAM-1 and LFA-1 [182]. This evidence concerns the gene ICAM1 and infection.