CCND1 and benign neoplasm: In addition, Wrobel et al. reported the overexpression of various Wnt pathway-correlated genes, such as CTNNB1, Cyclin-Dependent Kinase 5 Regulatory Subunit 1 (CDK5R1), Cyclin D1 (CCND1), and Ectodermal-Neural Cortex 1 (ENC1) in atypical and anaplastic MGs, relative to benign tumors [160].