Interestingly, there have also been reports of in vitro assays showing that a variety of different cell lines from different tumour types (lung cancer, squamous cell carcinoma, bladder carcinoma, glioblastoma, astrocytoma and kidney cancer) show increased proliferation through EGFR and ERK signalling when treated with THC [12]. The gene discussed is EGFR; the disease is urinary bladder carcinoma.