To explore autophagy, in this study, we analyzed LC3-II by Western blot in AML cells pretreated or not with U0126 and, then, treated by Q or with Rap in the presence of or in the absence of Bafilomycin A1 (Baf), which was added during the last 3 h. This evidence concerns the gene LRPAP1 and acute myeloid leukemia.