DOCK8 and hyperinsulinemic hypoglycemia, familial, 4: Comparable to almost all earlier observations [2,3,4,21,24], we recognized a greater frequency of eczema/atopic dermatitis in CID patients due to the consistent presence of eczema in hyper IgE syndrome and DOCK8 deficiency [18], that is, one of the main gene defects in our patients with cutaneous manifestations.