Recent long‐read sequencing technology has solved these problems, as evidenced by the discovery of noncoding CGG repeat expansions of NOTCH2NLC, FMR1, and NUTM2B‐AS1 in three leukoencephalopathies patients based on long‐read sequencing technology.7, 11, 35, 36. This evidence concerns the gene NUTM2B and Leukoencephalopathy.