Indeed, Nakano et al. [29] have indicated that D2-like receptor antagonist haloperidol significantly induces accumulation of IL-6+ and IL-17+ T cells with exacerbated cartilage destruction in RA synovial/SCID mouse chimera model, whereas D1-like receptor antagonist SCH-23390 strongly suppresses these responses. Here, IL17A is linked to rheumatoid arthritis.