INS and type 2 diabetes mellitus: In a study of 219,000 adults with T2D on the UK Primary Care Clinical Practice Research Datalink database in 2019, 15% (95% CI 14.1–15.9) were prescribed insulin as monotherapy, and for dual and triple therapy, 25.5% (95% CI 25.5–26.4) and 16.2% (95% CI 15.7–16.7), respectively [8].