Although our previous clinical investigation showed that acute myeloid leukemia (AML) patients with high levels of SCUBE1 expression had worse overall and disease-free survival rates [44], we were unable to detect genetic gains or amplifications of SCUBE1 in either AML or myelodysplastic syndrome cohorts (http://cbioportal.org). Here, SCUBE1 is linked to myelodysplastic syndrome.