TAFAZZIN and Barth syndrome: In this study, we prepared a white mutant strain of D. melanogaster, w1118, as a control and a homozygous TAZ-deficiency mutant strain (TAZ−/−), which exhibits Barth syndrome-related phenotypes, such as having a significant reduction in cardiolipin, mitochondrial abnormalities, and the degradation of muscle activity (Xu et al, 2006).