In all the animals, the stroke-induced neuronal loss, as determined by lack of NeuN (marker of mature neurons) immunoreactivity, was restricted to the cortex (mostly somatosensory cortex [S1FF and S1BL] and motor area [M1]), sparing subcortical structures (Palma-Tortosa et al., 2020). The gene discussed is RBFOX3; the disease is stroke disorder.