Moreover, there also some genes associated with malignant skin tumors, such as the gene of proteasome activator subunit 1 (PSME1) [33], proteasome activator subunit 2 (PSME2) [34], which is located near the fourth significant CNVR-CNV64, and docking protein 2 (DOK2) [35], which is located near CNV234 on chromosome 14. Here, PSME2 is linked to skin cancer.