Interestingly, the comparison of IgA/M, IgM, and IgA OD450 ratios among the three subject groups, namely dengue-primed and dengue-unprimed ZIKV-infected patients and HDs, revealed that there were significant differences among the subjects for IgA/M (p = 0.024) and IgA (p = 0.037) OD450 ratios, but not for IgM OD450 ratios (p = 0.222) (Figure 2). The gene discussed is CD40LG; the disease is dengue disease.