These enhancer–gene pairs included CDK6, [a key regulator of cell cycle and other tumor-promoting programs (26)], SNED1 [a metastasis-promoting gene associated with poor prognosis of triple-negative breast cancer (27)], and MTDH [a gene involved in breast cancer initiation, metastasis, and drug resistance (28)]. The gene discussed is CDK6; the disease is triple-negative breast carcinoma.