Some correlated pairs included bta-miR-2478 with SMIM7, bta-miR-574 with TRADD, HDHD2 and HSF1, and bta-miR-2332 with MAX in the FH group; and bta-miR-1260b with ERAS, bta-miR-2332 with SEC63 and HIF1A in the SFH group, exhibited a high negative correlation (r = 0.9). The gene discussed is TRADD; the disease is familial hyperaldosteronism.