Using an in vivo system specific to assess their osteogenic potential, AML-MSCs exhibit a reduced capacity to form mature bone and develop an osteoprogenitor-rich niche with the presence of Osterix+/OCN− pre-OBs and OCN+/Dentin matrix acid phosphoprotein 1− immature osteocytes.78 Here, BGLAP is linked to acute myeloid leukemia.