CSNK2B and common variable immunodeficiency: TNFRS13B (p.Ala181Glu: #35, CC: common variable immunodeficiency); CSNK2B (p.Arg47*: #39, CC: neurodevelopmental disease), ASMT (chrXp22.33p22.33×1 [1,529,000-1,644,000], 115-kb pseudo autosomal region deletion: #31); Multiple genes including IgG2 (chr14q32.33q32.33×1 [105,613,590-105,729,866], 115 kb that crosses 10 genes: #20, CC: frequent infections, resolved on IVIg); Multiple genes (15q11.2×1 [22,815,306-23,217,514], 42 kb: #6, CC: intellectual disability, but also can be explained by other variants)