Significantly higher levels of serum IL-6 (404.54 ± 543.38 vs 185.11 ± 242.73 pg/ml), IL-2 (5.30 ± 2.03 vs 4.11 ± 1.67 pg/ml), and IL-4 (4.76 ± 1.31 vs 3.34 ± 1.37 pg/ml) were found in patients with KD combined with severe sepsis (all P<0.05, respectively). This evidence concerns the gene IL4 and Sepsis.