P2RY12 and epilepsy: A study was reported on the association of single nucleotide polymorphisms (SNPs) in the P2Y12R gene with epilepsy, and it was found that carriers of the G allele of rs1491974 G>A or rs6798347 G>A may be associated with increased risk of epilepsy, with the rs1491974 G> A genotype and allele frequency differing significantly in females only, and individuals with this genotype may be exposed to more frequent seizures (Wang et al., 2022).