P2RY12 and epilepsy: Microglia are intrinsic immune cells of the central nervous system that mediate neuroinflammation, on which, P2Y12 receptor (P2Y12R) is mainly expressed in the central nervous system (CNS); Thus, P2Y12R plays an influential pathophysiological role in the neuroinflammatory response to epilepsy and is potentially valuable for the diagnosis and treatment of epilepsy.