We found that AGT from a diffusible fraction of hot water extract of ABM showed antitumor activity against leukemia cell lines U937, MOLT4, HL60, and K562,7 and revealed that AGT induces apoptosis in U937 cells.11 In this study, we examined the antitumor effects of AGT on K562, HL60, THP-1, and H929 cells to understand the mechanism behind AGT’s effects. This evidence concerns the gene AGT and leukemia.