NPPB and diabetes mellitus: On Cox multivariable analysis, log BNP (adjusted HR [aHR], 2.59; 95% CI, 1.81–3.72; p<0.0001) and log urinary albumin (aHR, 2.27; 95% CI, 1.82–2.84; p<0.0001) were identified as independent predictors for cardiovascular–renal events after adjusting for sex, age, systolic blood pressure, hemoglobin, HDL-cholesterol, LDL-cholesterol, eGFR, history of CVD, and diabetes (Table 6).