NCALD and colorectal carcinoma: The results of mechanistic experiments showed that CAFs-derived exosomes could inhibit 5-FU sensitivity in CRC cells via METTL3/miR-181d-5p/neurocalcin delta (NCALD) axis (111) CricN4BP2L2 was enriched in the exosomes of CAFs and could be delivered to LoVo cells and promote oxaliplatin resistance and stemness in LoVo cells while inhibiting apoptosis.