Mechanistic experiments turned out that CAFs-EVs can carry SNHG3 into CRC cells and upregulate HuR expression by competitively binding to miR-34b-5p, which in turn promotes the binding of HuR and HOXC6 and enhances the transcription of HOXC6 and promotes the malignant progression of CRC (122). The gene discussed is ELAVL1; the disease is colorectal carcinoma.