ZBTB2 and colorectal carcinoma: In addition, CRC cell-derived exosomal miR-146a-5p and exosomal miR-155-5p were delivered to CAFs and promoted the activation of CAFs by targeting cytokine signaling 1 (SOCS1) and zinc finger and BTB domain containing 2 (ZBTB2)-containing cells and regulating JAK2-STAT3/NF-κB signaling.