WWOX and colorectal carcinoma: The results of mechanistic experiments show that WEE2 antisense RNA 1 (WEE2-AS1) inhibits the Hippo pathway and thus CRC cell growth by binding MOB1A and promoting its degradation (127) CAFs-Exo can deliver miR-625-3p to CRC cells and promote CRC cell migration, invasion, EMT and chemoresistance by inhibiting the CELF2/WWOX pathway (128).