Nevertheless, pain in the tongue or inside the cheeks was the single independent predictor of Model 3 of atopic dermatitis diagnosis (OR = 3.6). A recent study suggested that the oral cavity may have a role in atopic dermatitis [18], and studies have demonstrated that children with atopic dermatitis had worse dental health than children without atopic dermatitis [11,19]. Considering 60% of atopic dermatitis patients had a mutation in the filaggrin gene (FLG), which is expressed in the oral mucosa [20]. This evidence concerns the gene FLG and atopic eczema.