HTR2A and psychotic disorder: In this context, the potential role of CB1 receptors in modulating the release of neurotransmitters (dopamine, serotonin and glutamate; Howlett et al. (2004)) implicated in schizophrenia and psychosis have been shown (Sawa and Snyder 2003), thus suggesting that SCs can indirectly modulate a variety of psychosis-related receptors (D2, 5-HT2A and NMDA; Fantegrossi et al. 2018).