Although Atf3 expression has been reported in proliferating AT2 cells in mice infected with Streptococcus pneumoniae (Ali et al., 2022), we did not observe an increase in Atf3-positive AT2 cells or in Atf3-positive mesenchymal cells following influenza infection (Figure 2—figure supplement 2A, B). Here, ATF3 is linked to influenza.