Our data are consistent with the results of Gholipour et al. [32], who demonstrated a 20E-mediated increase in the activity of superoxide dismutase (SOD), catalase (CAT), Glutathione Peroxidase (GPx), and Glutathione Reductase (GRx) in neurons of an amyloid-beta-induced rat model of Alzheimer’s disease. Here, GLRX is linked to early-onset autosomal dominant Alzheimer disease.