As an example, a drug combination or a standardized plant extract containing artemisinin (a potent anti-malarial molecule), artennuin B (a CYP3A4 inhibitor, but also showing a direct anti-malarial activity), quercetin (with direct anti-malarial activity and an inhibitor of thioredoxin reductase and anti-inflammatory), yomogiartemin (a gametocidal molecule) and thujone (has an direct anti-malarial effect and a CYP2A6 and CYP2B6 inhibitor) could be of potential interest in treating malaria. This evidence concerns the gene CYP3A4 and malaria.