Finally, we measured the antitumour activity, viability (Sulforhodamine B), and cathepsin B inhibition of natural and synthetic compounds in ACHN (Mus musculus kidney carcinoma, CRL-1611), Hepa-1c1c7 (Mus musculus liver carcinoma, CRL-2026) as tumour cell lines, and TKPTS (Mus musculus kidney normal, CRL-3361) and FL83B (Mus musculus liver normal, CRL-2390) as non-tumour cell lines. This evidence concerns the gene CTSB and neoplasm.