Among these, AKT serine/threonine protein kinase 1 (AKT1), which has the strongest binding capacity to luteolin and quercetin, is the main target of GBLs and plays a key role in the inhibition of apoptosis.[42] Neuronal apoptosis, especially in hippocampal neurons, is the main cause of symptoms of dementia. Here, CDK7 is linked to dementia.