The results obtained by De Amorin et al. (2013) [22], who used a DNA vaccine (pcDNA3-P10), Th1-related cytokines remained high during treatment, in addition to the increase in IL-10, and with this cytokine profile, although distinct from those found in our study, the mice that received the pcDNA3-P10 largely resolved their infections. Here, IL10 is linked to infection.