TLR4 and staphylococcus aureus infection: Meanwhile, the down-regulated pathways in the NS versus HS group consisted of “Lysosome” (1.72%), “Toll and IMD signaling pathway” (1.23%), and “Staphylococcus aureus infection” (0.03%), but were especially strong in “Glucagon signaling pathway” (0.95%) and “Growth hormone synthesis, secretion, and action” (0.92%) (Table S8).