The relationship between the administration of inhaled corticosteroids and candidiasis is mainly due to the decreases in salivary IgA and histamine due to the actions of immunosuppressants, considering that only 20% of the inhaled dose actually reaches the lungs, so most of the inhaled drug remains in the oral cavity and oropharynx, affecting the physiology of the oral tissues, in addition to suppressing cellular immunity and phagocytosis. The gene discussed is CD79A; the disease is candidiasis.