JNK and P13/AKT signaling pathways are induced in osteosarcoma cells via axes lncRNA CAT104—miR-381—mRNA ZEB1 [75], lncRNA MEG3—miR 127—mRNA ZEB1 [76], and lncRNA ATB—miR-200—mRNA ZEB1 and ZEB2 [77]. The gene discussed is MAPK8; the disease is osteosarcoma.