This finding is in line with recent evidence from molecular and cellular studies reporting abnormalities in a series of autophagic genes, such as AMPK, ULK1, AKT, MTOR, and BECN1, that block several steps of the autophagic process, some of which were reported as being relevant in the development of MDSs and their transformation to AML [16]. The gene discussed is BECN1; the disease is acute myeloid leukemia.