The data from the current study provide partial but important evidence that polymorphisms in apoptotic genes Bcl-2-938C>A and Bax-248G>A and pro-inflammatory cytokines IL-8 rs4073 T>A and TNF-α rs1800629 G>A may help predict the clinical outcomes of patients with leukemia. This evidence concerns the gene CXCL8 and leukemia.