AHR and ovarian carcinoma: The activation of AhR by TCDD in wild-type human ovarian cancer A2780 cells and cisplatin-resistant cells (A2780cis) indicates that AhR mediates the properties, self-renewal, and maintenance of CSCs and metastatic potential by launching PI3K/Akt and Wnt/β-catenin signaling pathways and mediates chemoresistance by preventing apoptosis [125].