Lately, in chronic myeloid leukemia cell lines, a regulatory interaction between AhR and the Dvl protein, which plays a central role in β-catenin stabilization, has been demonstrated; this interaction manifests itself as a dependence of AhR protein expression on the silencing or overexpression of Dvl [182]. Here, AHR is linked to chronic myelogenous leukemia, BCR-ABL1 positive.