At this stage, it is premature to exclude autoimmune mechanisms in dogs with epilepsy and dyskinesia of unknown origin based on negative test results for neural antibodies with assays expressing murine and human neural antigens, considering that we included one dog with epilepsy and a history of a teratoma, which is frequently associated with NMDAR1 antibodies in humans.47 This evidence concerns the gene GRIN1 and drug-induced dyskinesia.