We therefore selected Rab4-, Rab11- and Rab25-associated proteins from our dataset that had not previously been implicated in cell migration and/or invasion for further analysis in cells that lack Rab25 (A2780-DNA3 cells, in which migration is supported by Rab4; Christoforides et al., 2012) and Rab11 (Gemperle et al., 2022), or express Rab25 at levels similar to those found in ovarian cancer (Cheng et al., 2004) (A2780-Rab25) and migrate in a Rab25/α5β1-dependent manner (Caswell et al., 2007; Dozynkiewicz et al., 2012). The gene discussed is RAB4B; the disease is ovarian carcinoma.