MUC5AC and colonic neoplasm: Bresalier et al. found that in metastatic colon cancer, mucin sialic acid Tn antigen and sialic acid T antigen increased in metastases, and sialylated epitope antibodies or desialylation produced an effect that inhibited adhesion of metastatic cells to the basement membrane, indicating that increased sialylation of mucin-associated carbohydrates is the most likely feature of metastasizing colon cancer [55].