CDH1 and cancer: GnT-III overexpression is believed to enhance E-cadherin-related cell‒cell adhesion and downregulate integrin-mediated cell migration, which may help to inhibit cancer cell metastasis; [108] however, GnT-III expression is increased in gliomas, which seems to contradict its effect as a metastasis suppressor, [109] and Lu et al. attributed the controversy to the divergent expression patterns of cellular sialylation [107].