EGFR and glioma: Another study showed that FUT8, an enzyme that catalyzes the transmission of fucose residues from the donor substrate 5’-diphosphate-beta-L-fucose to the reducing terminal GlcNAc of the asparagine-linked oligosaccharide core structure, [115] is an important regulator of malignant features of human gliomas, and its knockdown or overexpression corresponds to a decrease and increase in the binding of lens culinaris agglutinin (LCA) to mesenchymal-epithelial transition factor (MET) and EGFR in glioma cells and affects the migration and invasion of glioma cells [96].