IL6 and obesity due to melanocortin 4 receptor deficiency: At the same time, the serum concentration of IL-6 in obesity group was significantly higher than that in control group and overweight group (2.81 ± 0.39pg/ml in the normal body weight group, 3.19 ± 0.87pg/ml in the overweight group, and 4.47 ± 0.41pg/ml in the obesity group).