IL6 and obesity due to melanocortin 4 receptor deficiency: The concentrations of IL-6 and CRP in GCF in the obesity group (IL-6: 5.23 ± 1.91pg/ml; CRP:5.19 ± 1.97 μg/ml) were significantly higher than those in the overweight (IL-6:4.29 ± 1.02pg/ml; CRP:4.34 ± 1.15 μg/ml)and normal weight (IL-6:4.15 ± 1.16pg/ml; CRP:4.29 ± 1.17 μg/ml) groups, with statistically significant differences (P < 0.05), but there was no statistically significant difference between the overweight and normal weight groups (P > 0.05) (Fig. 2).