CDH17 and neoplasm: We found that ‘ENSG00000136698’ is involved in signaling during embryonic development, and mutations in this gene may cause autosomal visceral heterotaxy and congenital heart disease; the cadherins encoded by ‘ENSG00000113361’ are essential for cell differentiation and morphogenesis, decreased expression of this gene may be related to tumor growth and metastasis; and ‘ENSG00000122691’ is important for embryonic development, and mutations in this gene would result in Saethre-Chotzen syndrome.