Based on stepwise logistic regression, the selected variables for the in-hospital mortality prediction algorithm were as follows: log odds of mortality = 16.287329 + 0.013572 × age- 0.447131 × CHF + 0.010371 × SAPSIII + 0.018552 × HR- 0.016852 × MBP + 0.049526 × RR- 0.286100 × temperature- 0.086035 × SPO2- 0.135393 × GCS- 0.530986 × COPD + 0.137646 × HCT- 0.461777 × HB- 0.067713 × bicarbonate + 0.007738 × BUN + 0.025168 × sodium. This evidence concerns the gene MBP and chronic obstructive pulmonary disease.