ANKRD12 and Dysarthria: Similarly, the PheWAS for ANKRD12 identified 11 phenome-wide significant associations including dysarthria and anarthria (motor disorders with speech deficit; International Classification of Diseases 10th Revision (ICD-10) code R47.1; P = 2.28 × 10−9), which suggests a potential mechanism of how ANKRD12 might affect VNR and EDU.